Molecular Diagnosis of Clear Cell Sarcoma

Molecular genetics, diagnosis and management of clear cell sarcoma of hand

Synonyms: Clear cell sarcoma of soft tissue, Clear cell sarcoma of the tendons and aponeuroses, malignant melanoma of the soft parts. Background: Rodriguez-Martin, Ortiz-Cruz, Del Rio, Vivanco, & Lopaz-Amor in 2011 stated “Clear cell sarcoma is a high-grade soft tissue sarcoma seen in adolescents and young adults, with melanosytic differentiation typically involving tendons and aponeuroses”. Cl...

Clear cell sarcoma of the hand: a case of malignant melanoma of soft parts

A case is reported with clear cell sarcoma (CCS) of the hand. Early diagnosis of clear cell sarcoma is always difficult due to its slow growing nature, benign clinical appearance, lack of pigmentation in most cases, and relatively young age of patients which make it to clinically appear as a benign soft tissue tumor. We report a case of clear cell sarcoma of hand in a 56 year old male with a no...

Clear cell sarcoma of the parotid region.

1 MD (Resident ENT Physician at EPM-UNIFESP). 2 MD, Head and Neck Surgeon (MD, Head and Neck Surgeon at EPM-UNIFESP). 3 MD, ENT, Head and Neck Surgeon (MD, ENT, Head and Neck Surgeon at EPM UNIFESP). 4 MSc on Pathology at EPM-UNIFESP (Professor in the Department of Pathology at EPM-UNIFESP). 5 Adjunct Professor in the Department of Otorhinolaryngology and Head and Neck Surgery at EPM-UNIFESP (V...

Soft tissue tumors: Clear cell sarcoma

Primary Clear-Cell Sarcoma in the Mediastinum

We report a case of primary clear-cell sarcoma (CCS) in the mediastinum. In October 2011, a 63-year-old man was admitted to our hospital for surgical resection. The tumor was completely excised by video-assisted thoracoscopic surgery. The tumor was well encapsulated and did not invade the pleura. Histological examination led to a final diagnosis of primary CCS in the mediastinum. The patient re...